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montgomery stuart a treatment resistant depression

Montgomery Stuart A. Treatment-Resistant Depression montgomery stuart a treatment resistant depression

Montgomery Stuart A....

Successful management of patients with treatment-resistant depression...

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Linda Gask ABC of Anxiety and Depression montgomery stuart a treatment resistant depression

Linda Gask ABC of An...

ABC of Anxiety and Depression is a practical guide to the assessment,...

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Carolyn Schniering A. Evidence-Based CBT for Anxiety and Depression in Children and Adolescents. A Competencies Based Approach montgomery stuart a treatment resistant depression

Carolyn Schniering A...

Evidence-Based CBT is the first book to take an explicitly competencie...

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Alan Carr Depression and Attempted Suicide in Adolescents montgomery stuart a treatment resistant depression

Alan Carr Depression...

It aims to provide the practitioner with a description of depression,...

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Allen Rubin Treatment of Depression in Adolescents and Adults. Clinician's Guide to Evidence-Based Practice montgomery stuart a treatment resistant depression

Allen Rubin Treatmen...

Praise for Treatment of Depression in Adolescents and Adults «This out...

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Peter Fisher Treating Depression. MCT, CBT and Third Wave Therapies montgomery stuart a treatment resistant depression

Peter Fisher Treatin...

A practical and conceptual guide to treating depression using both Bec...

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Lynne Walsh Depression Care Across the Lifespan montgomery stuart a treatment resistant depression

Lynne Walsh Depressi...

Depression Care across the Lifespan is a comprehensive, practical text...

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Lynne Walsh Depression Care Across the Lifespan montgomery stuart a treatment resistant depression

Lynne Walsh Depressi...

Depression Care across the Lifespan is a comprehensive, practical text...

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Lucy Maud Montgomery A Tangled Web montgomery stuart a treatment resistant depression

Lucy Maud Montgomery...

Lucy Maud Montgomery A Tangled Web

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Norman Sartorius Depression and Heart Disease montgomery stuart a treatment resistant depression

Norman Sartorius Dep...

Recently, there has been a growing awareness of the multiple interrela...

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Mary Codey Jo Postpartum Depression For Dummies montgomery stuart a treatment resistant depression

Mary Codey Jo Postpa...

It's a great blessing when a new mom with postpartum depression (PPD)...

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Norman Sartorius Depression and Cancer montgomery stuart a treatment resistant depression

Norman Sartorius Dep...

Recently, there has been a growing awareness of the multiple interrela...

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Andres Kanner Depression in Neurologic Disorders. Diagnosis and Management montgomery stuart a treatment resistant depression

Andres Kanner Depres...

Depression in Neurologic Disorders Diagnosis and Management Edited by...

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Wes Montgomery Wes Montgomery - Full House montgomery stuart a treatment resistant depression

Wes Montgomery Wes M...

Wes Montgomery Wes Montgomery - Full House

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Dr Brogan Kelly A Mind of Your Own: The Truth About Depression and How Women Can Heal Their Bodies to Reclaim Their Lives montgomery stuart a treatment resistant depression

Dr Brogan Kelly A Mi...

Depression is one of the UK’s leading causes of disability. One in fou...

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Brian Thomson Managing Depression with CBT For Dummies montgomery stuart a treatment resistant depression

Brian Thomson Managi...

Rise above depression with CBT Cognitive Behavioural Therapy (CBT) is...

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Для информации:

Successful management of patients with treatment-resistant depression is going to require a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors: with gene variants accounting for 50% of the variance in the clinical outcomes of antidepressant treatments this is clearly a fruitful area of research. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, predicts that genetic prediction of TRD could became a widespread clinical reality within a few years. Most patients with TRD will be treated pharmacologically and three chapters review the latest evidence for pharmacological best practice, including switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, revealing that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in TRD and summarizes general therapeutic principles.