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a new lease of death

Bollen Math H. Integration of Distributed Generation in the Power System a new lease of death

Bollen Math H. Integ...

The integration of new sources of energy like wind power, solar-power,...

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Цена: 10222.76 RUR

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Seraphima Nickolaevna Bogomolova Puzzled a new lease of death

Seraphima Nickolaevn...

A rendezvous in a Notting Hill café, a mystery of the digits 6-6-6, a...

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Цена: 320 RUR

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Code Name Verity a new lease of death

Code Name Verity

Oct. 11th, 1943-A British spy plane crashes in Nazi-occupied France. I...

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Цена: 729 RUR

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700 Classroom Activities a new lease of death

700 Classroom Activi...

This is a book which does exactly what it says on the cover. It provid...

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Цена: 2169 RUR

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Focus on Grammar 2: Workbook a new lease of death

Focus on Grammar 2:...

The fourth edition builds on the success of FOCUS ON GRAMMAR'S unique...

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Цена: 999 RUR

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The Art Of Surrender a new lease of death

The Art Of Surrender...

Jude Ryan expects obedience. And she always gets it. Fellow artist, Mi...

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Цена: 579 RUR

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Andre Rieu: Welcome To My Word. Episodes 9-11 a new lease of death

Andre Rieu: Welcome...

Episode 9: Down UnderAndre enjoys a whistle stop tour of Australia tre...

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Цена: 1499 RUR

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Montgomery Stuart A. Treatment-Resistant Depression a new lease of death

Montgomery Stuart A....

Successful management of patients with treatment-resistant depression...

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Цена: 3535.37 RUR

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Primack Richard B. Tropical Rain Forests. An Ecological and Biogeographical Comparison a new lease of death

Primack Richard B. T...

The first edition of Tropical Rain Forests: an Ecological and Biogeogr...

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Цена: 11530.09 RUR

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Andrew Hiles The Definitive Handbook of Business Continuity Management a new lease of death

Andrew Hiles The Def...

With a pedigree going back over ten years, The Definitive Handbook of...

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Цена: 4587.14 RUR

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Mark Tennant The Learning Self. Understanding the Potential for Transformation a new lease of death

Mark Tennant The Lea...

Praise for The Learning Self «In this age of self-help, the 'self' is...

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Цена: 2752.28 RUR

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Lilly Haines-Gadd TRIZ For Dummies a new lease of death

Lilly Haines-Gadd TR...

Use TRIZ to unlock creative problem solving Are you new to TRIZ and lo...

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Цена: 1965.26 RUR

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Calvin Dytham Choosing and Using Statistics. A Biologist's Guide a new lease of death

Calvin Dytham Choosi...

Choosing and Using Statistics remains an invaluable guide for students...

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Цена: 1831.58 RUR

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Very First Book of Things to Spot at Home a new lease of death

Very First Book of T...

A colourful and chunky book full of busy scenes around the house, with...

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Цена: 619 RUR

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Keith Johnson Acoustic and Auditory Phonetics a new lease of death

Keith Johnson Acoust...

Fully revised and expanded, the third edition of Acoustic and Auditory...

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Цена: 3273.25 RUR

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Virtue Ethics and Professional Roles a new lease of death

Virtue Ethics and Pr...

Taking medical and legal practice as key examples, the authors develop...

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Цена: 4595 RUR

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Для информации:

Successful management of patients with treatment-resistant depression is going to require a thorough understanding of the biological basis for both the depression and its failure to respond to standard treatments. This book clearly and succinctly summarizes the latest scientific research and its applications in clinical practice. A first step is a clear definition of what constitutes treatment-resistant depression so that clinical trials and other studies are using common criteria, enabling comparison and meta-analysis of their outcomes. The opening chapter reviews definitions and predictors of originating from different fields and discusses their usefulness in clinical practice and clinical research. The next chapter proposes a new definition, adapting terminology from medicine. Biological classification requires identification of genetic risk factors: with gene variants accounting for 50% of the variance in the clinical outcomes of antidepressant treatments this is clearly a fruitful area of research. Chapter 3 describes several genes already associated with treatment-resistant depression and, while further work is needed to translate findings into clinical recommendations, predicts that genetic prediction of TRD could became a widespread clinical reality within a few years. Most patients with TRD will be treated pharmacologically and three chapters review the latest evidence for pharmacological best practice, including switching strategies for antidepressants, the role of antipsychotics and augmentation strategies to complement lithium. There are two major alternatives to pharmacotherapy: neuromodulation and psychotherapy. The brain intervention chapter summarizes clinical research and experience with electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, deep brain stimulation and magnetic seizure therapy. The final chapter reviews the literature pertaining to the effectiveness of various forms of psychotherapy in patients who have not responded to antidepressant pharmacotherapy, revealing that patients who have not responded to one or two trials of antidepressant medication have a 30%-50% chance of responding to a focused psychotherapy. It proposes indications for psychotherapy in TRD and summarizes general therapeutic principles.