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a new lease of death

The Poetics of Comme...

The Poetics of Commemoration

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The Death of Archie

The Death of Archie

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The Death of Santini...

The Death of Santini

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The Necessary Death...

The Necessary Death of Lewis Winter

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Happiness, Death &am...

Happiness, Death & the Remainder of Life

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Opening the gates of...

Opening the gates of death: Channels in mitochondria

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A Dance with Dragon

A Dance with Dragon

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The Death of Santini...

The Death of Santini

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Death of Dracula

Death of Dracula

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The Death of Ivan Il...

The Death of Ivan Ilyich

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The Tick of Death

The Tick of Death

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Las intermitencias d...

Las intermitencias de la muerte

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Eagles Of Death Meta...

Eagles Of Death Metal Eagles Of Death Metal - Zipper Down

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Death of Wolverine

Death of Wolverine

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Teen Titans: Volume...

Teen Titans: Volume 3: Death of the Family

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Bran New Death

Bran New Death

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Для информации:

Mitochondria are vital cell organelles which sustain cellular life by acting as energy factories in a normal cell. Under certain circumstances, mitochondria turn into the gateways to death by releasing death-inducing proteins into the cytosol. The channels in the mitochondrial outer membrane that allow the efflux of the death-inducing proteins from mitochondria into the cytosol are unknown. My graduate research work was focused on understanding the nature of these channels both structurally and functionally. I discovered that the lipid called ceramide and the protein called Bax act together to facilitate protein release from mitochondria. My work shed further insights into how ceramide forms channels. I also explored the dynamics of channel formation by Bax. I developed ionic strength as a useful diagnostic tool study Bax channel formation in vitro.